Machine learning to detect Alzheimer's diesease from circulating non-coding RNAs

Ludwig N, Fehlmann T, Kern F, Gogol M, Maetzler W, Deutscher S, Gurlit S, Schulte C, von Thaler A-K, Deuschle C, Metzger F, Berg D, Suenkel U, Keller V, Backes C, Lenhof H-P, Meese E, Keller A

Genomics, Proteomics & Bioinformatics 2019 (accepted for publication)

 

Gait Analysis with Wearables Predicts Conversion to Parkinson Disease

Del Din S, Elshehabi M, Galna B, Hobert MA, Warmerdam E, Suenkel U, Brockmann K, Metzger F, Hansen C, Berg D, Rochester L, Maetzler W

Ann Neurol 2019;86:357-367

 

Detecting lung tumors from circulating microRNA profiles

Fehlmann T, Kahraman M, Ludwig N, Laufer T, Backes C, Galata V, Keller V, Geffers L, Mercaldo N, Roeske A, Duesterloh A, Hornung D, Weis T, Kayvanpour E, Abu-Halima M, Deuschle C, Schulte C, Suenkel U, von Thaler A-K, Maetzler W, Herr C, Faehndrich S, Vogelmeier C, Guimaraes P, Hecksteden A, Meyer T, Metzger F, Diener C, Deutscher S, Abdul-Khaliq H, Stehle I, Haeusler S, Meiser A, Groesdonk HV, Volk T, Lenhof H-P, Katus H, Balling R, Meder B, Krueger R, Huwer H, Bals R, Meese E, Keller A

JAMA Onc, Jul 2019 (accepted for publication)

 

Orthostatic hypotension as a risk factor for longitudinal detoriation of cognitive function in elderly

Zimmermann M, Wurster I, Lerche S, Roeben B, Machetanz G, Suenkel U, von Thaler A-K, Eschweiler G, Fallgatter A, Maetzler W, Berg D, Brockmann K

European Journal of Neurology. 2019, 0:1-8

 

Machine learning to detect Alzheimer`s disease from circulating non-coding RNAs

Ludwig N, Fehlmann T, Gogol M, Maetzler W, Deutscher S, Gurlit S, Schulte C, von Thaler A-K, Deuschle C, Metzger F, Berg D, Suenkel U, Keller V, Backes C, Lenhof H-P, Meese E, Keller A

bioRxiv. 2019 May

 

Prodromal features of Parkinson's disease: Self-reported symptoms versus clinically assessed signs

Friederich A, Flinspach A, Suenkel U, Eschweiler GW, Greulich K, TREND study team, Maetzler W, Berg D,

Heinzel S

Mov Disord. 2019 Jan;34(1):144-146

 

Arm swing asymmetry in overground walking

Killeen T, Elshehabi M, Filli L, Hobert MA, Hansen C, Rieger D, Brockmann K, Nussbaum S, Zörner B, Bolliger M, Curt A, Berg D, Maetzler W

Sci Rep. 2018 Aug 24;8(1):12803

 

Deterioration of executive dysfunction in elderly with REM sleep behavior disorder (RBD)

Lerche S, Machetanz G, Roeben B, Wurster I, Zimmermann M, von Thaler A-K, Liepelt-Scarfone I, Eschweiler G, Fallgatter A, Metzger F, Maetzler W, Berg D, Brockmann K

Neurobiology of Aging 70 (2018) 242-246.

 

Effect of physical activity on cognitive flexibility, depression and RBD in healthy elderly.

Lerche S, Gutfreund A, Brockmann K, Hobert MA, Wurster I, Suenkel U, Eschweiler GW, Metzger FG, Maetzler W, Berg D

Clin Neurol Neurosurg. 2018 Jan 9; 165: 88-93.

 

Gait is associated with cognitive flexibility: A dual-tasking study in healthy older people

Hobert MA, Meyer SI, Hasmann SE,  Metzger FG, Suenkel U, Eschweiler GW, Berg D, Maetzler W

Front. Aging Neurosci. May 2017;9,:154.

 

Structural Ultrasound of the Medial Temporal Lobe in Alzheimer's Disease

Yilmaz R, Pilotto A, Roeben B, Preische O, Suenkel U, Heinzel S,  Metzger FG, Laske C, Maetzler W, Berg D

Ultraschall in Med 2017; 38-294-300.

 

Application of the movement disorder society prodromal Parkinson's disease research criteria in 2 indeprendent prospective cohorts.

Pilotto A, Heinzel S, Suenkel U, Lerche S, Brockmann K, Roeben B, Schaeffer E, Wurster I, Yilmaz R, Liepelt-Scarfone I, von Thaler A-K, Metzger FG, Eschweiler GW, Postuma RB, Maetzler W, Berg D

Movement Disorders 2017 Jul; 32(7): 1025-1034.

 

Evidence for a Selectively Regulated Prioritization Shift Depending on Walking Situations in Older Adults

Salkovic D, Hober MA, Bellut C, Funer F, Renno S, Haertner L, Hasmann S, Staebler J, Geritz J, Suenkel U, Fallgatter AJ, Eschweiler GW, Berg D, Maetzler W

Front. Aging Neurosci.April 2017;9:75.

 

Associations between early markers of Parkinson's disease and sarcopenia

Drey M, Hasmann SE, Krenovsky J, Hobert MA, Straub S, Elshehabi M, von Thaler A-K, Fallgatter AJ, Eschweiler GW, Suenkel U, Berg D, Maetzler W

Front. Aging Neurosci.March 2017;9:53.

 

Cognitive Performance Patterns in Healthy Individuals with Substantia Nigra Hyperechogenicity and Early Parkindon's Disease

Rezzak Y, Gräber S, Roeben B, Suenkel U, von Thaler A-K, Heinzel S., Methger FG, Eschweiler GW, Maetzler W, Berg D and Liepelt-Scarfone I

Front. Aging Neurosci.November 2016;8:271.

 

Prospective longitudinal course of cognition in older subjects with mild parkinsonian signs.

Lerche S, Brockmann K, Pilotto A, Wurster I, Sünkel U, Hobert MA, von Thaler A-K, Schulte C, Stoops E, Vanderstichele H, Herbst V, Brix B, Eschweiler GW, Metzger FG, Maetzler W, Berg D

Alzheimers Res Ther. 2016 Oct 10;8(1):42.

 

Dual Tasking for the Differentiation between Depression and Mild Cognitive Impairment.

Metzger FG, Hobert MA, Ehlis A-C, Hasmann SE, Hahn T, Eschweiler GW, Berg D, Fallgatter AJ, Maetzler; TREND study team.

Front. Aging Neurosci. 2016 Sep 8:235.

 

Association of Plasma Aβ40 Peptides, But Not Aβ42, with Coronary Artery Disease and Diabetes Mellitus

Roeben B, Maetzler W, Vanmechelen E, Schulte C, Heinzel S, Stellos K, Godau J, Huber H, Brockmann K, Wurster I, Gaenslen A, Grüner E, Niebler R, Eschweiler GW, Berg D; TREND study team.

J Alzheimers Dis. 2016 Mar 16;52(1):161-9.

 

State-dependent altered connectivity in late-life depression: a functional near-infrared spectroscopy study
Rosenbaum D, Hagen K, Deppermann S, Kroczek A M, Haeussinger F B, Heinzel S, Berg D, Fallgatter A J, Metzger F G, Ehlis A-C, the TREND study Consortium.

Neurobiology of Aging 39 (2016)57-68.

Age and Vascular Burden Determinants of Cortical Hemodynamics Underlying Verbal Fluency
Heinzel S, Metzger, FG, Ehlis, A-C, Korell R, Alboji A, Haeussinger F B, Wurster I, Brockmann K, Suenkel U, Eschweiler GW, Maetzler W, Berg D, Fallgatter AJ.

PLoS One. 10(9): e0138863 September 22, 2015.

Reasons for mild parkinsonian signs - which constellation may indicate neurodegeneration?
Lerche S, Brockmann K, Wurster I, Gaenslen A, Roeben B, Holz D, Eschweiler GW, Maetzler W, Berg D. Parkinsonism Relat Disord. 2015 Feb 21 (2):126-30.

The relation of SMI and the VSEP in a risk sample for neurodegenerative disorders
Hagen K, Ehlis AC, Haeussinger FB, Beeretz S, Kromer GV, Heinzel S, Maetzler W, Eschweiler GW, Berg D, Fallgatter AJ, Metzger FG, The TREND Study Consortium.

J Neural Transm. 2014 Dec 18.

Prodromal features for Parkinson's disease - baseline data from the TREND study
Gaenslen A, Wurster I, Brockmann K, Huber H, Godau J, Faust B, Lerche S, Eschweiler GW, Maetzler W, Berg D. Eur J Neurol. 2014 May;21(5):766-72

Mild parkinsonian signs in the elderly - is there an association with PD? Crossectional findings in 992 individuals
Lerche S, Hobert M, Brockmann K, Wurster I, Gaenslen A, Hasmann S, Eschweiler GW, Maetzler W, Berg D.

PLoS One. 2014 9(3):e92878.
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A neurodegenerative vascular burden index and the impact on cognition
Heinzel S, Liepelt-Scarfone I, Roeben B, Nasi-Kordhishti I, Suenkel U, Wurster I, Brockmann K, Fritsche A, Niebler R, Metzger RG, Eschweiler GW, Fallgatter AJ, Maetzler W, Berg.

Front Aging Neurosci. 2014 Jul 9;6:161
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Lowered serum amyloid-ß 1-42 autoantibodies in individuals with lifetime depression.
Maetzler W, Langkamp M, Lerche S, Godau J, Brockmann K, Gaenslen A, Huber H, Wurster I, Niebler R, Eschweiler GW, Berg D.

Journal of Alzheimer's Disease 2012 Jul 5

Aging-related cortical reorganization of verbal fluency processing: an NIRS study
Heinzel S, Metzger FG, Ehlis A-C, Korell R, Alboji A, Haeussinger FB, Hagen K, Maetzler W, Eschweiler GW, Berg D, Fallgatter AJ and the TREND study consortium. Neurobiology of Aging 2012 Jul 5

Poor trail making test performance is directly associated with altered dual task prioritization in the elderly-baseline results from the TREND study.
Hobert MA, Niebler R, Meyer SI, Brockmann K, Becker C, Huber H, Gaenslen A, Godau J, Eschweiler GW, Berg D, Maetzler W.

PLoS One. 2011;6(11):e27831
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